
Secura Bio is powering the next commercial chapter for oncology medicines. We are built to rapidly accelerate opportunity discovery and amplify a drug’s value from the moment we acquire it. We believe the core capabilities necessary to achieve that outcome include:
Driving Better Outcomes in Oncology
Maximizing the commercial impact of oncology therapies, especially for tough-to-treat patient populations, is challenging for many reasons. Patient groups are often small and heterogeneous. There’s often limited clinical data. This creates a paradox where both scientific precision and scalable access strategies must be balanced to address the high unmet need.
The Secura Bio team has decades of experience navigating these complexities to shape the impact of some of oncology’s largest clinical and market opportunities. Our success is built on four habits engrained in our cross-functional, customer-facing teams:
- Understand the challenges of treating oncology patients, particularly in the most difficult-to-treat populations
- Listen to feedback about what’s working and what is not
- Take action to address challenges swiftly and effectively
- Work with our global team to expand the possibilities to help the most patients
On this foundation, Secura Bio has proven our ability to optimize sales for approved indications and pioneer clinical trial protocols in T cell cancers to address significant unmet need.
Our High-Touch Difference
Too often, lack of experience in a sophisticated commercial marketplace, an inability to maximize commercial success with a clinical development plan, and sluggish response times lead to missed opportunities to generate value. We’ve created a high-touch commercialization approach to ensure every value-driving possibility can be unlocked.
Patient-Centered Clinical Strategy
We leave no stone unturned to find the patients who will benefit most from our therapies. We leverage our biomarker-driven clinical development and regulatory science capabilities to optimize patient stratification and investigate intriguing observations from our field teams and insights from our clinical trials.
We are working diligently to expand our flagship therapy, duvelisib, into peripheral T cell lymphoma (PTCL) based on clinical data, which indicate the drug may have potential to benefit patients with T-Follicular Helper subtype; an underserved patient group.
The Power of Patient StratificationTERZO Trial
When we acquired duvelisib, the drug had been evaluated in a Phase 1 trial that included patients with peripheral T cell lymphoma (PTCL). PTCL is a rare and aggressive type of non-Hodgkin lymphoma with limited treatment options. The five-year survival rate is well below 50%, highlighting the need for life-saving and life-prolonging medicines for these patients.
We continued development of duvelisib in PTCL by conducting a large Phase 2 trial, the PRIMO trial. In the trial, we focused heavily on patient stratification to identify subpopulations of patients with PTCL who may benefit most from the duvelisib. Based on the results of the PRIMO trial, we are now conducting a Phase 3 trial in patients with lymphomas originating from the T follicular helper (TFH) cell.
As the first to run a Phase 3 trial in these indications, we worked closely with regulators to design a protocol to address this disease with significant unmet needs. To read more about the TERZO trial, or to read the published results of the PRIMO trial that drove our interest in TFH lymphoma, please visit our Clinical Research and Development page.